isotope dilution वाक्य
उदाहरण वाक्य
मोबाइल
- By 2006, isotope dilution mass spectrometry ( IDMS ) became the reference method.
- In addition, unlike traditional analytical methods which rely on signal intensity, isotope dilution employs signal ratios.
- Instead of isotope dilution, a known mass of stable carrier ion is added to radionuclide sample solution.
- "' Isotope dilution analysis "'is a method of determining the quantity of chemical substances.
- Isotope dilution involves the addition of a known amount of radionuclide tracer to the sample that contains a known stable element.
- To simplify the selection of internal standard, most laboratories use an analogous stable isotope in an isotope dilution type analysis.
- In the 1930s, US biochemist David Rittenberg pioneered the use of isotope dilution in biochemistry enabling detailed studies of cell metabolism.
- ICP-MS also lends itself to quantitative determinations through isotope dilution, a single point method based on an isotopically enriched standard.
- Owing to both of these advantages, the method of isotope dilution is regarded among chemistry measurement methods of the highest metrological standing.
- Most clinical laboratories now align their creatinine measurements against a new standardized isotope dilution mass spectrometry ( IDMS ) method to measure serum creatinine.
- In its most simple conception, the method of isotope dilution comprises the addition of known amounts of isotopically-enriched substance to the analyzed sample.
- Mixing of the isotopic standard with the sample effectively " dilutes " the isotopic enrichment of the standard and this forms the basis for the isotope dilution method.
- Isotope dilution is classified as a method of internal standardisation, because the standard ( isotopically-enriched form of analyte ) is added directly to the sample.
- An early application of isotope dilution in the form of radiotracer method was determination of the solubility of lead sulphide and lead chromate in 1913 by George de Hevesy and Friedrich Adolf Paneth.
- When calibration plots are markedly nonlinear, one can bypass the empirical polynomial fitting and employ the ratio of two linear functions ( known as Pad?approximant ) which is shown to describe the curvature of isotope dilution curves exactly.
- The NKDEP program in the United States has attempted to solve this problem by trying to get all laboratories to calibrate their measures of creatinine to a " gold standard ", which in this case is isotope dilution mass spectrometry ( IDMS ).
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